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Hong, Cynthia

0000-0002-2563-219X

A5004070525 | I1344073410

Mayo Clinic

Howard Hughes Medical Institute

Citations 1

The E3 ubiquitin ligase Idol controls brain LDL receptor expression, ApoE clearance, and Aβ amyloidosis

Science Translational Medicine | November 18, 2015 | Volume: 7 | Issue: 314 | Pages: No page available

10.1126/scitranslmed.aad1904 | PMID 26582899

Inhibiting the E3 ubiquitin ligase Idol in a mouse model of Alzheimer’s-like pathology ameliorates disease severity by promoting clearance of Aβ peptides by microglia.