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Tolosa, Ezequiel

Mayo Clinic

Precision Cancer Therapeutics, Center for Individualized Medicine, Mayo Clinic Rochester MN 55905 USA mansfield.aaron@mayo.edu.

Citations 1

Fluorescence based live cell imaging identifies exon 14 skipped hepatocyte growth factor receptor (MET) degraders

RSC Advances | April 4, 2025 | Volume: 15 | Issue: 13 | Pages: 10419-10425

10.1039/d5ra01441g | PMID 40182503

Despite ongoing efforts to employ structure-based methods to discover targeted protein degraders (TPD), the prevailing strategy remains synthesizing a focused set of heterobifunctional compounds and screening them for target protein degradation.