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Cannone, Valentina

0000-0002-5168-8381

Mayo Clinic

Cardiorenal Research Laboratory, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, United States.

Citations 2

MANP: A natriuretic peptide-based therapy for cardiometabolic disease

MANP: A natriuretic peptide-based therapy for cardiometabolic disease | June 5, 2024 | Volume: No volume available | Issue: No issue available | Pages: No page available

10.14293/cgmp.24000035.v1

Sex-based differences in metabolic protection by the ANP genetic variant rs5068 in the general population

American Journal of Physiology-Heart and Circulatory Physiology | July 7, 2023 | Volume: 325 | Issue: 3 | Pages: H545-H552

10.1152/ajpheart.00321.2023 | PMID 37417873

Males are characterized by lower ANP and BNP with greater prevalence of cardiometabolic disease. The ANP genetic variant rs5068 was associated with less metabolic dysfunction in males, whereas no metabolic profile was related to the BNP genetic variant rs198389 in the general population. ANP may play a more biological role in metabolic homeostasis compared with BNP in the general population with greater physiological metabolic actions in males compared with females.