Harki, Daniel A

0000-0001-5950-931X

Mayo Clinic

Department of Chemistry, University of Minnesota, 207 Pleasant Street SE, Minneapolis, Minnesota 55455, United States.

Citations 2

A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes

Journal of Medicinal Chemistry | January 10, 2022 | Volume: 65 | Issue: 3 | Pages: 2342-2360

10.1021/acs.jmedchem.1c01779 | PMID 35007061

Synthesis of a peptide-universal nucleotide antigen: towards next-generation antibodies to detect topoisomerase I-DNA covalent complexes

Organic & Biomolecular Chemistry | April 13, 2016 | Volume: 14 | Issue: 17 | Pages: 4103-4109

10.1039/c5ob02049b | PMID 27113574

A peptide-universal nucleotide conjugate that mimics the topoisomerase I-DNA covalent complex was synthesized and then utilized to raise monoclonal antibodies.