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Pais, Gwendolyn M

0000-0003-4961-0048

Mayo Clinic

Midwestern University-Downers Grove Campus, Department of Pharmacy Practice, Downers Grove, Illinois, USA.

Citations 2

Iohexol-Measured Glomerular Filtration Rate and Urinary Biomarker Changes between Vancomycin and Vancomycin Plus Piperacillin-Tazobactam in a Translational Rat Model

Antimicrobial Agents and Chemotherapy | July 10, 2023 | Volume: 67 | Issue: 8 | Pages: No page available

10.1128/aac.00304-23 | PMID 37428202

Recent clinical studies have reported additive nephrotoxicity with the combination of vancomycin and piperacillin-tazobactam. However, preclinical models have failed to replicate this finding.
Glomerular Function and Urinary Biomarker Changes between Vancomycin and Vancomycin plus Piperacillin-Tazobactam in a Translational Rat Model

Antimicrobial Agents and Chemotherapy | January 10, 2022 | Volume: 66 | Issue: 3 | Pages: No page available

10.1128/aac.02132-21 | PMID 35007142

Clinical studies have reported additive nephrotoxicity associated with the combination of vancomycin (VAN) and piperacillin-tazobactam (TZP). This study assessed differences in glomerular filtration rate (GFR) and urinary biomarkers between rats receiving VAN and those receiving VAN + TZP.