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Coppola, Giovanni

0000-0003-2105-1061

Mayo Clinic

Departments of Psychiatry and Neurology, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Citations 1

AD-linked R47H- TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation

Science Translational Medicine | December 1, 2021 | Volume: 13 | Issue: 622 | Pages: No page available

10.1126/scitranslmed.abe3947 | PMID 34851693

R47H- TREM2 mutation enhances AKT signaling in human AD microglia and mediates proinflammatory and synaptic toxicity in a tauopathy mouse model.