Back to Authors

Telpoukhovskaia, Maria

0000-0002-5237-4042

Mayo Clinic

Gladstone Institute of Neurological Disease, San Francisco, CA 94107, USA.

Citations 1

AD-linked R47H- TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation

Science Translational Medicine | December 1, 2021 | Volume: 13 | Issue: 622 | Pages: No page available

10.1126/scitranslmed.abe3947 | PMID 34851693

R47H- TREM2 mutation enhances AKT signaling in human AD microglia and mediates proinflammatory and synaptic toxicity in a tauopathy mouse model.