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Botha, Hugo

0000-0003-4390-685X

Mayo Clinic

Department of Neurology, Mayo Clinic, Rochester, MN.

Citations 68

Tau-negative amnestic dementia masquerading as Alzheimer disease dementia

Neurology | February 7, 2018 | Volume: 90 | Issue: 11 | Pages: No page available

10.1212/wnl.0000000000005124 | PMID 29438037

FDG-PET in tau-negative amnestic dementia resembles that of autopsy-proven hippocampal sclerosis

Brain | February 7, 2018 | Volume: 141 | Issue: 4 | Pages: 1201-1217

10.1093/brain/awy049 | PMID 29538658

Facial diplegia after pembrolizumab treatment

Muscle & Nerve | April 11, 2017 | Volume: 56 | Issue: 3 | Pages: No page available

10.1002/mus.25663 | PMID 28398689

NeuroDebian Virtual Machine Deployment Facilitates Trainee-Driven Bedside Neuroimaging Research

Journal of Child Neurology | September 21, 2016 | Volume: 32 | Issue: 1 | Pages: 29-34

10.1177/0883073816668113 | PMID 27655470

Freely available software, derived from the past 2 decades of neuroimaging research, is significantly more flexible for research purposes than presently available clinical tools. Here, we describe and demonstrate the utility of rapidly deployable analysis software to facilitate trainee-driven translational neuroimaging research. A recipe and video tutorial were created to guide the creation of a NeuroDebian-based virtual computer that conforms to current neuroimaging research standards and can exist within a HIPAA-compliant system. This allows for retrieval of clinical imaging data, conversion to standard file formats, and rapid visualization and quantification of individual patients’ cortical and subcortical anatomy. As an example, we apply this pipeline to a pediatric patient’s data to illustrate the advantages of research-derived neuroimaging tools in asking quantitative questions “at the bedside.” Our goal is to provide a path of entry for trainees to become familiar with common neuroimaging tools and foster an increased interest in translational research.
A Young Man With Progressive Language Difficulty and Early-Onset Dementia

JAMA Neurology | March 28, 2016 | Volume: 73 | Issue: 5 | Pages: 595

10.1001/jamaneurol.2016.0246 | PMID 27019131

Teaching Neuro Images : Massive cerebral edema after CT myelography

Neurology | October 27, 2014 | Volume: 83 | Issue: 18 | Pages: No page available

10.1212/wnl.0000000000000946 | PMID 25349278

Clinical Reasoning: A woman with subacute progressive confusion and gait instability

Neurology | July 29, 2014 | Volume: 83 | Issue: 5 | Pages: No page available

10.1212/wnl.0000000000000648 | PMID 25074896

Nonverbal oral apraxia in primary progressive aphasia and apraxia of speech

Neurology | April 12, 2014 | Volume: 82 | Issue: 19 | Pages: 1729-1735

10.1212/wnl.0000000000000412 | PMID 24727315