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Wurdak, Heiko

0000-0003-4385-4324

Mayo Clinic

Leeds Institute of Cancer and Pathology, Faculty of Medicine and Health, University of Leeds, St James's University Hospital, Beckett Street, Leeds, West Yorkshire LS9 7TF, UK.

Citations 1

Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade

Science Translational Medicine | January 3, 2018 | Volume: 10 | Issue: 422 | Pages: No page available

10.1126/scitranslmed.aam7577 | PMID 29298869

Intravenous infusion of oncolytic reovirus in patients leads to infection of brain tumors, infiltration by cytotoxic T cells, and up-regulation of PD-L1.