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Robichaud, Jielu Hao

Mayo Clinic

WinnMed

Citations 1

Kidney organoids demonstrate that PTH1R drives a cystogenic cAMP-pPKA-pCREB axis in developmental polycystic kidney disease

American Journal of Physiology-Renal Physiology | July 2, 2025 | Volume: 329 | Issue: 2 | Pages: F257-F268

10.1152/ajprenal.00056.2025 | PMID 40602764

Stem cell-derived kidney organoids enable human genetic disease modeling to identify the parathyroid hormone 1 receptor as a potential new therapeutic target for developmental polycystic kidney disease.