Abstract Introduction Penile enhancement procedures are becoming more common in men looking to achieve a more desirable penile aesthetic. We describe a case of post-procedural dermatitis after receiving penile girth enhancement injections in an adult male and discuss management of penile girth injection side effects. Materials and Methods We review and present our case alongside a discussion of girth injection complications. Results Patient's exam and symptoms improved after treatment. Conclusion Post-procedural complications after penile girth injections seem to be under-reported and unfortunately can result in severe deformity and dysfunction of the penis.