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Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis
Zhu, Changyu , Kim, KyeongJin , Bartolomé, Alberto , Salomao, Marcela , Dongiovanni, Paola , Meroni, Marica , Graham, Mark J., Yates, Katherine P. , Diehl, Anna Mae , Schwabe, Robert F. , Tabas, Ira , Valenti, Luca , Lavine, Joel E. , Bartolome, Alberto , Salomao, Marcela , Dongiovanni, Paola , Yates, Katherine P , Diehl, Anna Mae , Schwabe, Robert F , Tabas, Ira , Valenti, Luca , Pajvani, Utpal B. , Wang, Xiaobo

Science Translational Medicine | November 21, 2018 | Volume: 10 | Issue: 468 | Pages: No page available

10.1126/scitranslmed.aat0344 | PMID 30463916 Get It

Aberrant hepatocyte Notch activation is required for development of NASH-associated fibrosis, and Notch inhibition ameliorates obesity-induced liver disease.