Citations

Background: Chronic hip abductor insufficiency remains a challenging problem to treat and can result in significant disability in some patients. Tendon transfers involving the gluteus maximus (GM) or combined GM with tensor fascia latae (GM+TFL) are common options for surgical reconstruction. The purpose of this systematic review was to compare clinical outcomes, complications, and revisions rates of patients who underwent GM transfer or GM+TFL transfer for irreparable hip abductor tears. Methods: PubMed (MEDLINE), Scopus (EMBASE, MEDLINE, COMPENDEX), and Cochrane databases were used to conduct a systematic review of articles from inception to February 2025. A total of 18 studies were included (11 GM transfer, 7 GM+TFL transfer). Demographics, hip setting (native hip, primary total hip arthroplasty [THA], revision THA), patient-reported outcome measures, presence of Trendelenburg gait, abduction strength, complication rates, and revision rates were analysed. Results: A total of 207 patients (208 hips) underwent GM transfer, while 55 patients (55 hips) underwent GM+TFL transfer. Meta-analyses demonstrated that both techniques yielded significant preoperative to postoperative improvements in modified Harris Hip Scores/Harris Hip Scores and Visual Analogue Scale pain scores ( p < 0.001). In total, 33.9% of patients who underwent GM transfer had a persistent Trendelenburg gait postoperatively, compared to 48.1% of those who underwent GM+TFL transfer. The complication rate was 16.8% (23/137) for patients who underwent GM transfer and 2.7% (1/37) for those who underwent GM+TFL transfer; while revision rates were 5.9% (9/152) and 3.6% (2/55), respectively. Conclusions: Both GM and GM+TFL transfers yielded comparable outcomes in patients with chronic hip abductor insufficiency not amendable to primary repair. The complication rate was substantially higher in patients who underwent GM transfer, whereas revision rates were comparably low for both techniques. In particular, a sizeable proportion of patients continued to exhibit a persistent Trendelenburg gait postoperatively following both surgical techniques, highlighting the complexity of this pathology. PROSPERO registration number: CRD420251002466

Targeted delivery of magnetic nanoparticles (MNPs) to an area of a blood vessel with fluidic flow is hampered by the lack of a suitable real‐time imaging modality for MNPs, the control system complexity, and low targeting performance. Herein, an offline programming guidance (OLPG) scheme for aggregated MNPs is proposed based on a real‐time aggregation volume estimator. The proposed aggregation volume estimator based on a magnetic drug‐targeting simulator reflects volume changes of aggregated MNPs; hence, it can model a magnetic force acting on aggregated MNPs in real time while enhancing targeting performance. The proposed guidance system is evaluated using a simulation testbed and in vitro model of the rat brain, which yields comparable results at different fluid viscosities, flow velocities, target areas, and flow types. The OLPG with the aggregation volume estimator improves targeting performance by 116%–409% compared with the default mode, and by 111%–180% compared to the performance without the aggregation volume estimator. Furthermore, a guidance margin predicts enhanced targeting performance (root‐mean‐square error < 5%) irrespective of the flow environment. The proposed guidance strategy has the potential to overcome the problems caused by the lack of an imaging modality, control‐system complexity, and low targeting performance.