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119 citation(s) found for "Syrjanen, Jeremy".

F2‐02‐01: NEUROFILAMENT LIGHT CHAIN IN AD IN CSF AND BLOOD
Syrjanen, Jeremy A. , Blennow, Kaj , Hagen, Clinton E., Petersen, Ronald C. , Kern, Silke , Zetterberg, Henrik , Skoog, Ingmar , Wærn, Margda , Harten, Argonde C. van , Knopman, David S. , Jack, Clifford R. , Mielke, Michelle M.

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_11 | Pages: No page available

10.1016/j.jalz.2018.06.2615 Get It

P3‐238: LONGITUDINAL ASSOCIATIONS OF PLASMA NEUROFILAMENT LEVELS WITH AMYLOID‐PET, FDG‐PET, AND COGNITION AMONG NON‐DEMENTED PARTICIPANTS IN THE MAYO CLINIC STUDY ON AGING
Syrjanen, Jeremy A. , Blennow, Kaj , Hagen, Clinton E., Petersen, Ronald C. , Mielke, Michelle M. , Zetterberg, Henrik , Kern, Silke , Skoog, Ingmar , Machulda, Mary M. , Knopman, David S. , Jack, Clifford R.

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_22 | Pages: No page available

10.1016/j.jalz.2018.06.1597 Get It

P2‐430: MR SPECTROSCOPY FROM FRONTAL LOBE AND POSTERIOR CINGULATE GYRUS IN ASYMPTOMATIC AND SYMPTOMATIC MICROTUBULE‐ASSOCIATED PROTEIN TAU (MAPT) MUTATION CARRIERS
Chen, Qin , Brushaber, Danielle , Dheel, Christina, Fields, Julie A. , Forsberg, Leah K. , Gavrilova, Ralitza H. , Gearhart, Debra, Haley, Dana , Graff‐Radford, Jonathan , Graff‐Radford, Neill R. , Kraft, Ruth, Rademakers, Rosa , Syrjanen, Jeremy A. , Rosen, Howard J. , Boxer, Adam L. , Boeve, Bradley F. , Jones, David T. , Knopman, David S. , Lapid, Maria I. , Wszołek, Zbigniew K. , Kantarci, Kejal

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_16 | Pages: No page available

10.1016/j.jalz.2018.06.1122 Get It

P2‐273: CEREBROSPINAL FLUID NEUROFILAMENT LIGHT PROTEIN AND RISK OF MILD COGNITIVE IMPAIRMENT IN THE MAYO CLINIC STUDY OF AGING
Syrjanen, Jeremy A. , Blennow, Kaj , Hagen, Clinton E., Petersen, Ronald C. , Kern, Silke , Zetterberg, Henrik , Skoog, Ingmar , Wærn, Margda , Harten, Argonde C. van , Knopman, David S. , Jack, Clifford R. , Mielke, Michelle M.

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_14 | Pages: No page available

10.1016/j.jalz.2018.06.962 Get It

P1‐420: ACCELERATED NEUROCHEMICAL CHANGES PRIOR TO PHENOCONVERSION TO FRONTOTEMPORAL LOBAR DEGENERATION IN PRESYMPTOMATIC MICROTUBULE‐ASSOCIATED PROTEIN TAU (MAPT) MUTATION CARRIERS: A LONGITUDINAL MRS STUDY
Chen, Qin, Tosakulwong, Nirubol , Lesnick, Timothy G. , Brushaber, Danielle , Dheel, Christina, Fields, Julie A. , Forsberg, Leah K. , Gavrilova, Ralitza H. , Gearhart, Debra, Haley, Dana , Gunter, Jeffrey L. , Graff‐Radford, Jonathan , Graff‐Radford, Neill R. , Kraft, Ruth, Rademakers, Rosa , Syrjanen, Jeremy A. , Rosen, Howard J. , Boxer, Adam L. , Chen, Qin, Boeve, Bradley F. , Jones, David T. , Knopman, David S. , Lapid, Maria I. , Wszołek, Zbigniew K. , Kantarci, Kejal

Alzheimer's & Dementia | October 22, 2018 | Volume: 14 | Issue: 7S_Part_8 | Pages: No page available

10.1016/j.jalz.2018.06.429 Get It

Epidemiologic study of risk factors for meningioma in the Mayo Clinic Study of Aging.
Butts, Alissa M. , Syrjanen, Jeremy A. , Aakre, Jeremiah A. , Brown, Paul D. , Jack, Clifford R. , Petersen, Ronald C. , Roberts, Rosebud O., Cerhan, Jane H. , Jack, Clifford R

Journal of Clinical Oncology | September 6, 2018 | Volume: 35 | Issue: 15_suppl | Pages: 2067-2067

10.1200/jco.2017.35.15_suppl.2067 Get It

2067 Background: An estimated 2% of the general population has a meningioma (Vernooij et al. 2007), which accounts for about 36% of all primary intracranial tumors (Ostrom et al. 2015). The most established risk factors are older age and female gender. One small study identified gender but no other risk factors with meningioma (Krampla et al 2004). A larger study using the Iowa Women’s Health study data found lower levels of physical activity, greater body mass index (BMI), greater height and uterine fibroids were associated with meningioma (Johnson et al. 2011). We sought to replicate these findings and to identify additional risk factors related to meningioma in a large population-based sample. Methods: Study participants were enrolled in the Mayo Clinic Study of Aging (MCSA), a population-based sample of Olmsted County, Minnesota residents used to study prevalence, incidence, and risk-factors for Mild Cognitive Impairment and dementia and includes a variety of medical factors. Using a text search of radiologists’ notes of 2,402 MCSA individuals, mean age 77±8 years and scanned between 2004-2014.We identified 52 subjects who had at least one meningioma. We estimated the association of selected potential risk factors with presence of meningioma using odds ratios and 95% confidence intervals from logistic regression models adjusted for age and gender, which informed the multivariable models. Results: In the initial models, significant risk factors identified included BMI (as a continuous variable) (OR = 1.06 95%CI 1.01 to 1.12), taking NSAIDS (OR = 2.11, 95%CI 1.13 to 3.95), aspirin (OR = 1.90, 95%CI 1.04 to 3.46), and blood pressure lowering medication (OR = 2.06, 95%CI 1.07 to 3.99). Protective factors included male gender (OR = 0.51, 95%CI 0.29 to 0.90), coronary artery disease (CAD; OR = 0.46, 95%CI 0.22 to 0.97) and higher Beck Anxiety Inventory (BAI) total score (OR = 0.88, 95%CI 0.78 to 0.98). Simultaneous adjustment for these factors in a multivariable model did not attenuate these associations. Conclusions: Findings reveal gender and BMI as risk factors for meningioma. Additionally, certain medications such as NSAIDS and BP lowering medications warrant follow up as potential factors related to development of meningioma.