Citations 11
Comparison of a Novel, Rapid Chromogenic Biochemical Assay, the Carba NP Test, with the Modified Hodge Test for Detection of Carbapenemase-Producing Gram-Negative Bacilli
Vasoo, Shawn , Cunningham, Scott A. , Kohner, Peggy C., Simner, Patricia J. , Mandrekar, Jayawant N. , Lolans, Karen , Hayden, Mary K. , Patel, Robin , Patel, Robin , Cunningham, Scott A
Journal of Clinical Microbiology | July 4, 2013 | Volume: 51 | Issue: 9 | Pages: 3097-3101
ABSTRACT We compared carbapenemase detection among 271 Gram-negative bacilli (of which 131 were carbapenemase producers) using a novel chromogenic rapid test—the Carba NP test (CNP)—and the modified Hodge test (MHT). Sensitivities were comparable (CNP, 100%, versus MHT, 98%; P = 0.08), but CNP was more specific (100% versus 80%; P < 0.0001) and faster.