Citations 11
Alcohol Consumption and Development of Acute Respiratory Distress Syndrome: A Population-Based Study
Thakur, Lokendra , Kojicic, Marija, Thakur, Sweta, Pieper, Matthew S., Kashyap, Rahul , Trillo‐Alvarez, Cesar , Javier, Fernández, Cartin‐Ceba, Rodrigo , Vukoja, Marija , Kojicic, Marija, Gajic, Ognjen , Kashyap, Rahul
International Journal of Environmental Research and Public Health | September 11, 2009 | Volume: 6 | Issue: 9 | Pages: 2426-2435
This retrospective population-based study evaluated the effects of alcohol consumption on the development of acute respiratory distress syndrome (ARDS). Alcohol consumption was quantified based on patient and/or family provided information at the time of hospital admission. ARDS was defined according to American-European consensus conference (AECC). From 1,422 critically ill Olmsted county residents, 1,357 had information about alcohol use in their medical records, 77 (6%) of whom developed ARDS. A history of significant alcohol consumption (more than two drinks per day) was reported in 97 (7%) of patients. When adjusted for underlying ARDS risk factors (aspiration, chemotherapy, high-risk surgery, pancreatitis, sepsis, shock), smoking, cirrhosis and gender, history of significant alcohol consumption was associated with increased risk of ARDS development (odds ratio 2.9, 95% CI 1.3–6.2). This population-based study confirmed that excessive alcohol consumption is associated with higher risk of ARDS.