Citations 22
The NEALS primary lateral sclerosis registry
Chan, James , Thrower, Sara, Staff, Nathan P. , Datta, Neil, Kisanuki, Yaz Y. , Drory, Vivian E., Fournier, Christina , Goutman, Stephen A. , Atassi, Nazem , Group, On behalf of the NEALS PLS Registry Study, Jeon, Maryangel, Caldwell, Sarah, McDonough, Timothy, Gentile, Caroline, Liu, Jianing , Turner, M.F., Denny, Carol, Felice, Kevin J. , Green, Misty, Scarberry, Stephanie, Abu-Saleh, Saad, Nefussy, Beatrice, Hastings, Debbie, Kim, S. K., Swihart, Blake, Arcila-Londono, Ximena , Newman, Daniel S. , Silverman, Michael G. , Genge, Angela , Salmon, Kristiana , Elman, Lauren , McCluskey, Leo, Almasy, Kelly, Goslin, Kimberly, CUMMINGS, A. J., Edwards, Eli K., Rivner, Michael H. , Bouchard, Kristy, Quarles, Brandy, Kwan, Justin , Jaffa, Matthew , Baloh, Robert H. , Allred, Peggy, Walk, David , Maiser, Samuel, Manousakis, Georgios , Ferment, Valerie, Fernandes, J. Americo, Thaisetthawatkul, Pariwat , Heimes, Deborah, Sams, Laura, Kahler, Melissa, Corcoran, Alecia, Larriviere, Daniel G., Chotto, Sadie, Juba, Gracy, Staff, Nathan P , Turner, Michelle, Goutman, Stephen A , Walk, David , Paganoni, Sabrina , Marchi, Fabiola De , Pioro, Erik P. , Group, On behalf of the NEALS PLS Registry Study, Caldwell, Sarah, Mcdonough, Timothy, Turner, Michelle, Denny, C. Dimla, Newman, Daniel S., Silverman, Michael, Gotkine, Marc , Cummings, Arlena, Phillips, Melissa
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration | September 11, 2020 | Volume: 21 | Issue: sup1 | Pages: 74-81
Primary lateral sclerosis (PLS) functional rating scale: PLS‐specific clinimetric scale
Mitsumoto, Hiroshi , Chiuzan, Codruța , Gilmore, Madison , Zhang, Yuan , Simmons, Zachary , Kisanuki, Yasushi, Zinman, Lorne , Jawdat, Omar, Sorenson, Eric J. , Floeter, Mary Kay, Filho, J. Americo M. Fernandes, Heitzman, Daragh, Fournier, Christina , Oskarsson, Björn , Heiman‐Patterson, Terry , Maragakis, Nicholas J. , Joyce, Nanette C. , Hayat, Ghazala , Nations, Sharon , Scelsa, Stephen N. , Walk, David , Elman, Lauren , Hupf, Jonathan , McHale, Brittany , group, the PLSFRS study, Sorenson, Eric, Simmons, Zachary , Oskarsson, Björn , Maragakis, Nicholas , Walk, David , Paganoni, Sabrina , Pioro, Erik P. , group, the PLSFRS study
Muscle & Nerve | November 23, 2019 | Volume: 61 | Issue: 2 | Pages: 163-172
AbstractIntroductionOur research aim was to develop a novel clinimetric scale sensitive enough to detect disease progression in primary lateral sclerosis (PLS).MethodsA prototype of the PLS Functional Rating Scale (PLSFRS) was generated. Seventy‐seven participants with PLS were enrolled and evaluated at 21 sites that comprised the PLSFRS study group. Participants were assessed using the PLSFRS, Neuro‐Quality of Life (QoL), Schwab‐England Activities of Daily Living (ADL), and the Clinical Global Impression of Change scales. Participants completed telephone assessments at 12, 24, and 48 weeks after enrollment.ResultsThe PLSFRS demonstrated internal consistency as well as intrarater, interrater, telephone test‐retest reliability, and construct validity. Significant changes in disease progression were detected at 6 and 12 months; changes measured by the PLSFRS vs the ALSFRS‐R were significantly higher.DiscussionThe PLSFRS is a valid tool to assess the natural history of PLS in a shorter study period.