Citations 11
Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma
Zhu, Yuan Xiao , Braggio, Esteban , Shi, Chang-Xin, Kortuem, K. Martin, Bruins, Laura A., Schmidt, Jessica, Chang, Xiu-Bao, Langlais, Paul R. , Luo, Moulun , Jedlowski, Patrick , LaPlant, Betsy, Laumann, Kristina, Bergsagel, P. Leif , Lacy, Martha Q. , Champion, Mia D., Stewart, A. Keith, Bergsagel, P. Leif , Langlais, Paul, Lacy, Martha, Fonseca, Rafaël , Mıkhael, Joseph , Braggio, Esteban
Blood | June 10, 2014 | Volume: 124 | Issue: 4 | Pages: 536-545
Key PointsWe identified CRBN-binding proteins and confirmed recent work implicating the Ikaros transcription factors as important members. Low IZKF1 levels predict lack of IMiD responsiveness and shorter OS; IZKF1 expression is a potential predictive biomarker for clinic application.