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Lowe, Val J.

https://orcid.org/0000-0002-5612-1667

Mayo Clinic

Mayo Clinic

Citations 745

IC‐P‐028: CogState computerized testing is associated with amyloid and FDG‐PET: Implications for secondary preventive trials
Wiste, Heather J. , Weigand, Stephen D. , Lowe, Val J. , Roberts, Rosebud O., Petersen, Ronald C. , Mielke, Michelle M. , Vemuri, Prashanthi , Machulda, Mary M. , Knopman, David S. , Kantarci, Kejal , Geda, Yonas E. , Boeve, Bradley F. , Jack, Clifford R.

Alzheimer's & Dementia | October 9, 2013 | Volume: 9 | Issue: 4S_Part_1 | Pages: No page available

10.1016/j.jalz.2013.05.029 Get It

P3–217: Effect of intellectual lifestyle and Alzheimer's disease biomarkers on rate of cognitive decline: Mayo Clinic Study of Aging
Lesnick, Timothy G. , Przybelski, Scott A. , Lowe, Val J. , Roberts, Rosebud O., Gregg, Brian E., Gunter, Jeffrey L. , Petersen, Ronald C. , Vemuri, Prashanthi , Knopman, David S. , Machulda, Mary M. , Mielke, Michelle M. , Geda, Yonas E. , Senjem, Matthew L. , Jack, Clifford R.

Alzheimer's & Dementia | October 9, 2013 | Volume: 9 | Issue: 4S_Part_16 | Pages: No page available

10.1016/j.jalz.2013.05.1290 Get It

P4–086: Dramatic improvement with donepezil in a case of dementia with Lewy bodies
Allen, Laura A., Josephs, Keith A. , Ivnik, Robert J., Lowe, Val J. , Pittock, Sean J. , Smith, Glenn E. , Boeve, Bradley F.

Alzheimer's & Dementia | October 9, 2013 | Volume: 9 | Issue: 4S_Part_18 | Pages: No page available

10.1016/j.jalz.2013.05.1475 Get It

P3–093: FDG‐PET and PiB‐PET imaging in asymptomatic at‐risk carriers of a novel octapeptide repeat insertion in PRNP
Lowe, Val J. , Przybelski, Scott A. , Weigand, Stephen D. , Spychalla, Anthony J., Jones, David, Kumar, Neeraj , Rademakers, Rosa , Petersen, Ronald, Parisi, Joseph, Boeve, Bradley F. , Kantarci, Kejal , Vemuri, Prashanthi , Jones, David, McDade, Eric , Baker, Matthew , Knopman, David S. , Petersen, Ronald, Dickson, Dennis W. , Jack, Clifford R.

Alzheimer's & Dementia | October 9, 2013 | Volume: 9 | Issue: 4S_Part_14 | Pages: No page available

10.1016/j.jalz.2013.05.1163 Get It

Syndromes dominated by apraxia of speech show distinct characteristics from agrammatic PPA
Josephs, Keith A. , Senjem, Matthew L. , Lowe, Val J. , Whitwell, Jennifer L. , Duffy, Joseph R. , Strand, Edythe A. , Machulda, Mary M. , Jack, Clifford R. , Senjem, Matthew L

Neurology | June 27, 2013 | Volume: 81 | Issue: 4 | Pages: 337-345

10.1212/wnl.0b013e31829c5ed5 Get It

Application of the National Institute on Aging-Alzheimer's Association AD criteria to ADNI
Lowe, Val J. , Peller, Patrick J., Weigand, Stephen D. , Quintero, Catalina Montoya, Tosakulwong, Nirubol , Vemuri, Prashanthi , Senjem, Matthew L. , Jordan, Lennon, Petersen, Ronald C. , Jack, Clifford R. , Knopman, David S. , Vemuri, Prashanthi , Senjem, Matthew L

Neurology | May 4, 2013 | Volume: 80 | Issue: 23 | Pages: 2130-2137

10.1212/wnl.0b013e318295d6cf Get It

Microbleeds in the logopenic variant of primary progressive aphasia
Whitwell, Jennifer L. , Gunter, Jeffrey L. , Senjem, Matthew L. , Murphy, Matthew C. , Kantarci, Kejal , Lowe, Val J. , Josephs, Keith A. , Jack, Clifford R. , Duffy, Joseph R. , Strand, Edythe A. , Machulda, Mary M. , Senjem, Matthew L , Kantarci, Kejal

Alzheimer's & Dementia | April 4, 2013 | Volume: 10 | Issue: 1 | Pages: 62-66

10.1016/j.jalz.2013.01.006 Get It

Abstract Background Microbleeds have been associated with Alzheimer's disease (AD), although it is unclear whether they occur in atypical presentations of AD, such as the logopenic variant of primary progressive aphasia (lvPPA). We aimed to assess the presence and clinical correlates of microbleeds in lvPPA. Methods Thirteen lvPPA subjects underwent 3T T2*‐weighted and fluid‐attenuated inversion recovery magnetic resonance imaging and Pittsburgh compound B (PiB) positron emission tomography imaging. Microbleeds were identified on manual review and assigned a regional location. Total and regional white matter hyperintensity (WMH) burden was measured. Results Microbleeds were observed in four lvPPA subjects (31%), most commonly in the frontal lobe. Subjects with microbleeds were older, more likely female, and had a greater burden of WMH than those without microbleeds. The regional distribution of microbleeds did not match the regional distribution of WMH. All cases were PiB positive. Conclusions Microbleeds occur in approximately one third of subjects with lvPPA, with older women at the highest risk.
Brain β-amyloid load approaches a plateau
Wiste, Heather J. , Lesnick, Timothy G. , Weigand, Stephen D. , Vemuri, Prashanthi , Senjem, Matthew L. , Gunter, Jeffrey L. , Mielke, Michelle M. , Lowe, Val J. , Petersen, Ronald C. , Jack, Clifford R. , Knopman, David S. , Pankratz, V. Shane , Boeve, Bradley F. , Mielke, Michelle M , Vemuri, Prashanthi , Senjem, Matthew L

Neurology | March 1, 2013 | Volume: 80 | Issue: 10 | Pages: 890-896

10.1212/wnl.0b013e3182840bbe Get It

Lung Cancer Screening Experience: A Retrospective Review of PET in 22 Non-Small Cell Lung Carcinomas Detected on Screening Chest CT in a High-Risk Population
Lindell, Rebecca M. , Hartman, Thomas E. , Swensen, Stephen J., Jett, James R., Midthun, David E. , Nathan, Mark A., Lowe, Val J.

American Journal of Roentgenology | February 28, 2013 | Volume: 185 | Issue: 1 | Pages: 126-131

10.2214/ajr.185.1.01850126 Get It

Traffic Jam at the Blood–Brain Barrier Promotes Greater Accumulation of Alzheimer’s Disease Amyloid-β Proteins in the Cerebral Vasculature
Agyare, Edward K., Leonard, Sarah R., Curran, Geoffry L., Yu, Caroline C., Lowe, Val J. , Poduslo, Joseph F., Kandimalla, Karunya K. , Paravastu, Anant K. , Kandimalla, Karunya K

Molecular Pharmaceutics | December 18, 2012 | Volume: 10 | Issue: 5 | Pages: 1557-1565

10.1021/mp300352c Get It